a smartPAC
Contact Advanced Tissue

New Technique Could Increase Skin Graft Effectiveness

New Technique Could Increase Skin Graft Effectiveness

  by    0   1

New technique for wound healing with skin grafts

Scientists in Vienna have created a new technique to help wound healing with skin grafts.

As a review in the journal Wounds pointed out, humans have used skin grafts in some form for nearly 3,000 years. These days, transplanting skin grafts from one body part to another is common for extensive burn treatment. And while grafts have helped thousands of patients each year, they still have inherent setbacks, as Medscape explained. Those complications include infection, the formation of painful hematomas, wound contracture, and other occurrences that greatly delay proper wound healing.

However, a team from the Medical University of Vienna may have found a solution to some of the issues surrounding grafts.

White blood cells to the rescue

In a Scientific Reports study, the Vienna collective developed a post-transplant treatment involving the application of white blood cells. The treatment is meant to address grafts for older patients or those with conditions like diabetes, as these groups are more likely to experience delays in graft healing. Younger people, meanwhile, generally don’t have the same problems when it comes to post-op wound care.

So, to speed up skin graft healing, researchers irradiated the white blood cells of several lab animals, which cause them to become “stressed.” In this state, the white blood cells release several enzyme factors and proteins that help with tissue rebuilding and angiogenesis, or the creation of new blood vessels. The team then collected these various chemicals, synthesized them into a medicine and used them on lab animals with wounds.

Among the more promising results, the new medical compound resulted in more effective skin growth and doubled the usual number of blood vessels.

A promise for the future

While human trials have yet to begin, lead author Stefan Hacker said in an accompanying press release that this new technique could have huge implications.

“Clinical application in humans should not be restricted to burn injuries but can also work for other types of wounds,” he said. “For example it could be beneficial for poorly healing diabetic skin ulcers or for wounds after microsurgical tissue transplantation.”

If the Vienna team’s method does become available, it would make skin grafts even more of a viable option for patients. More recently, researchers across the globe have been looking into alternatives for skin grafts. That includes bioengineered skin, which has less risk of infection or scarring, and negative-pressure wound therapy, wherein circulation is increased to improve wound healing rates.


Advanced Tissue is a leading provider of specialized wound care products.

Download our FREE Wound Treatment Product Guide for more information on our wound care supplies.

Download Now

Related Posts

Scientists Blind Infection Bacteria In New Treatment Approach

This new method of combating infections could help millions of patients across the world who deal with drug-resistant bacteria.This method of combating infections could help millions of patients who deal with drug-resistant bacteria. For 2016 alone, the American Burn Association estimated that 486,000 people underwent treatment. As if burns weren’t already debilitating enough, many of these same people then have to deal with secondary infections that can prove especially complicated to treat.  In fact, […]


Doctors Treat Bleeds with Electrical Currents

Doctors treat bleeds with electrical currentsThe neural tourniquet is a groundbreaking way to treat injuries and bleeding disorders using advanced technology. According to the World Health organization, upwards of 5.8 million people worldwide die as a result of bodily injuries every year. A large percentage of those are due to blood loss, which is a continuing challenge for doctors to treat more […]


Cancer Cells Move Differently Than Other Types

Cancer cells move differently than other typesUnderstanding how cells move could help doctors develop treatments for cancer and improve wound healing therapies. Tumor cells are unlike other cell types for a number of different reasons, according to the Dana-Farber Cancer Institute. For one, they create energy by utilizing very specific metabolic pathways. They’re also able to turn off so-called tumor-suppressor genes, which […]


Healthy Cooking Tips to Use Everyday

Healthy cooking tips to use every dayHealthy cooking is often about planning ahead. If you’ve put any time into trying to maintain a healthy lifestyle, you likely know just how important the proper foods can be. What we consume on a daily basis can have a huge impact on our personal health, from lowering blood pressure and maintaining the immune system […]


Bamboo Used to Develop New Wound Care Dressing

Bamboo used to develop new wound care dressing (1)These new bamboo dressings were found to accelerate wound healing as well as prevent issue with odors. Anyone who has even the faintest insight might be aware of the sheer number of unique material types used in the wound care industry. There are the more traditional options, like collagen and hydrocolloid. While those options are […]


Leave a Reply

Your email address will not be published. Required fields are marked *

Back to Top